Dietary Oxalate Induces Urinary Nanocrystals in Humans Nanocrystal Paper Abstract Crystalluria is thought to be associated with kidney stone formation and can occur when urine becomes supersaturated with calcium, oxalate, and phosphate. The principal method used to identify urinary crystals is microscopy, with or without a polarized light source. This method can detect crystals aboveContinue reading “Kumar et. al publishes in Kidney International Reports”
Dr. Mitchell was awarded a NIH NIDDK R03 grant to study dietary oxalate and innate immunity in kidney stone disease! She is the first person to receive this award in her department!
Dietary Oxalate and Kidney Stone Formation Dietary Oxalate and Kidney Stone Formation Review Abstract Dietary oxalate is plant-derived and may be a component of vegetables, nuts, fruits, and grains. In normal individuals, approximately half of urinary oxalate is derived from the diet and half from endogenous synthesis. The amount of oxalate excreted in urine playsContinue reading “Mitchell et. al publishes review in AJP Renal”
The Mitchell laboratory welcomes Iliana Colvin to the lab! Iliana is an undergraduate student here at UAB!
The Mitchell laboratory welcomes Andrew Bell to the lab! Andrew is a part of the KURE (Kidney Undergraduate Research Experience) program, an NIH funded Summer Research Program!
Stay in the Loop: New Insights About Randall’s Plaques and Stone Disease Stay in the Loop Editorial
The Mitchell laboratory welcomes Dr. Parveen Kumar, PhD to the lab!
Oxalate induces mitochondrial dysfunction and disrupts redox homeostasis in a human monocyte derived cell line Oxalate and THP-1 Monocyte Paper Abstract Monocytes/macrophages are thought to be recruited to the renal interstitium during calcium oxalate (CaOx) kidney stone disease for crystal clearance. Mitochondria play an important role in monocyte function during the immune response. We recently determined that monocytes inContinue reading “Patel et. al publishes in Redox Biology”
Congratulations to Adam for being awarded “The Gateway to Research Award” from the American Foundation for Pharmaceutical Education with Dr. Robert Wang from Samford University McWhorter School of Pharmacy! Adam is the first student to receive this award at Samford!
The Mitchell Lab welcomes, Glory Akinduro, a UAB-Genentech Undergraduate Research Scholar for the summer!