Dr. Mitchell’s Publications on PubMed

  • Patel M, Yarlagadda V, Adedoyin O, Saini V, Assimos DG, Holmes RP, and Mitchell T. Oxalate induces mitochondrial dysfunction and disrupts redox homeostasis in a human monocyte derived cell line. Redox Biol. 2017 Dec; 15:207-215.
  • Chacko BK, Wall SB, Kramer PA, Ravi S, Mitchell T, Johnson MS, Wilson L, Barnes S, Landar A, and Darley-Usmar VM. Pleiotropic effects of 4-hydroxynonenal on oxidative burst and phagocytosis in neutrophils. Redox Biol. 2016 Jun 23;9:57-66
  • Williams J, Holmes RP, Assimos DG, and Mitchell T. Monocyte Mitochondrial Function in Calcium Oxalate Stone Formers. Urology. 2016 Jul;93:224.e1-6
  • Chacko BK, Zhi D, and Mitchell T. The Bioenergetic Health Index is Sensitive to Oxidative Stress in Human Monocytes. Redox Biol. 2016 Aug;8:43-50.
  • Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, Barnes S, Arabshahi A, Dell’Italia L, George D, Steele C, George J, Darley-Usmar VM, and Melby S. Hemoglobin-associated Oxidative Stress in the Pericardial Compartment of Post-operative Cardiac Surgery Patients. Lab Invest. 2015 Feb;95(2):132-41.
  • Ravi S§, Mitchell T§, Kramer PA, Chacko BK, and Darley-Usmar VM.  Mitochondria in Monocytes and Macrophages-Implications for Translational and Basic Research.  Int J Biochem Cell Biol. 2014 Aug;53:202-7. §Co-first authors.
  • Chacko BK, Kramer P, Ravi S, Benavides G, Mitchell T, Dranka BP, Ferrick D, Singal AK, Ballinger S, Bailey SM, Hardy R, Zhang J, Zhi D, Darley-Usmar VM. The Bioenergetic Health Index: A New Concept in Mitochondrial Translational Research. Clin Sci (Lond). 2014 Sep;127(6):367-73
  • Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, and Darley-Usmar VM. Bioenergetics and the Oxidative Burst: Protocols for the Isolation and Evaluation of Human Leukocytes and Platelets. J Vis Exp. 2014 Mar 27;(85).
  • Mitchell T, Johnson MS,  Ouyang X, Chacko BK, Mitra K, Lei X, Gai Y, Moore DR, Barnes S, Zhang J, Koizumi A, Ramanadham S, and Darley-Usmar VM. Dysfunctional autophagy and mitochondrial bioenergetics in a model of Type I diabetes mellitus. Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E585-99.
  • Reily C§, Mitchell T§, Chacko B, Benavides G, Murphy MP, Kalyanaraman B, and Darley-Usmar V. Mitochondrially targeted compounds and their impact on cellular bioenergetics. Redox Biology Journal 1(1): 86-93 (2013). §Co-first authors.
  • Mitchell T, Chacko B, Ballinger S, Bailey S, Zhang J, and Darley-Usmar V. Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: implications for mitochondrial therapeutics. Biochem Soc Trans. 2013 Feb 1;41(1):127-33.
  • Mitchell T, Chacko B, and Darley-Usmar V. Controlling Radicals in the Powerhouse: Development of MitoSOD. Chem Biol. 2012 Oct 26;19(10):1217-8.
  • Mitchell T, Darley-Usmar V. Metabolic syndrome and mitochondrial dysfunction: insights from pre-clinical studies with a mitochondrially targeted antioxidant. Free Radic Biol Med. 2012 Mar 1;52(5):838-40.
  • Parajuli N, Marine A, Simmons S, Saba H, Mitchell T, Shimizu T, Shirasawa T and MacMillan-Crow LA. Generation and characterization of novel kidney-specific manganese superoxide dismutase knockout mice. Free Radic Biol Med. 2011 Jul 15;51(2):406-16.
  • Mitchell T, Rotaru D, Saba H, Smith RAJ, Murphy MP, and MacMillan-Crow LA. The mitochondria-targeted antioxidant Mitoquinone protects against cold storage injury of renal tubular cells and rat kidneys. J Pharmacol Exp Ther. 2011 Mar;336(3):682-92.
  • Mitchell T, Saba H, Laakman J, Parajuli N, MacMillan-Crow LA.  Role of mitochondrial-derived oxidants in renal tubular cell cold-storage injury. Free Radic Biol Med. 2010 Nov 1;49(8):1273-82.
  • Munusamy S, Saba H, Mitchell T, Megyesi JK, Brock RW, MacMillan-Crow LA. Alteration of renal respiratory Complex-III during experimental type-1 diabetes. BMC Endocr Disord. 2009 Jan 23;9:2.
  • Saba H, Batinic-Haberle I, Munusamy S, Mitchell T, Lichti C, Megyesi J, and MacMillan-Crow LA. Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion. Free Radic Biol Med. 2007 May 15;42(10):1571-8.